The Sheffield Trophoblastic Disease Centre

The Centre was established in 1973, as part of a national programme, to screen for gestational trophoblastic tumours (a spectrum of disorders including hydatidiform mole and choriocarcinoma) for the North of England and North Wales.

This website offers information for women diagnosed with trophoblastic disease and for medical professionals caring for women with these rare disorders.

The Sheffield Trophoblastic Disease Centre is based at Weston Park Hospital in Sheffield. The centre is run in collaboration with the University of Sheffield and the Cancer Clinical Trials Centre at Weston Park Hospital. Information about the hospital and how to get here can be found on the Weston Park Hospital website.

The Gestational Trophoblastic Disease team at Weston Park Hospital. l-r  Annie Hills, Jane Ireson, Sarah Gillett, all Clinical nurse specialists, Matt Winter, Deputy Director of service, Kam Singh, Lead Clinical nurse specialist, Julie Ford, secretary, John Tidy, Director of service and Tracey Byne, secretary. Picture: Marie Caley


New guidelines for post pregnancy screening of hCG effective from 1st July 2017

Data analysis of more than 13,000 GTD patients in the UK shows that:
• The detection rate for recurrent GTD on routine post-pregnancy screening of women previously diagnosed with one molar pregnancy is extremely low.
• For women previously treated with GTN post pregnancy monitoring should still be continued.

· The national gestational screening service has deemed it safe to no longer require hCG monitoring for women post pregnancy who have had one previous molar pregnancy that has not required chemotherapy.

In the UK there are three centres involved in the screening programme for trophoblastic disease, the others are at Charing Cross Hospital in London and at Ninewells Hospital in Dundee. The Sheffield and London Centres also treat persistent tumours. Sheffield provides the service the service for the North of England and North Wales.
Logos of The University of Sheffield and Sheffield Teaching Hospitals NHS Trust